Asymmetric transfer hydrogenation of quinolines using tethered Ru(II) catalysts
نویسندگان
چکیده
0957-4166/$ see front matter 2010 Elsevier Ltd. A doi:10.1016/j.tetasy.2010.03.053 * Corresponding author. Tel.: +44 24 7652 3260; fa E-mail address: [email protected] (M. Wills) The first report of an asymmetric transfer hydrogenation, in formic acid/triethylamine, of quinolines is described. Using a Ru(II) catalyst containing a 4-carbon tether, products of up to 73% ee were formed, whilst a Rh(III)-tethered catalyst gave products of up to 94% ee. 2010 Elsevier Ltd. All rights reserved.
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تاریخ انتشار 2010